4 research outputs found
The prevalence of renal dysfunction in patients with coronary heart disease, coronary artery bypass surgery
Relevance. Despite the successes achieved in the treatment of coronary heart disease through the use of high-tech surgical methods of treatment, including coronary bypass surgery, the evaluation of the postoperative course of the disease, the search for facts affecting the progression of early and late cardiovascular complications remain relevant. Identifying early predictors of adverse outcomes is a critical task. The presence of renal dysfunction in the postoperative period after coronary artery bypass surgery is an important factor leading to a deterioration of the cardiorenal relationship. Purpose of the study. To assess the prevalence of renal dysfunction among patients with coronary heart disease in the postoperative period after coronary artery bypass surgery in conjunction with other cardiovascular risk factors.ΠΠΊΡΡΠ°Π»ΡΠ½ΠΎΡΡΡ. ΠΠ΅ΡΠΌΠΎΡΡΡ Π½Π° ΡΡΠΏΠ΅Ρ
ΠΈ, Π΄ΠΎΡΡΠΈΠ³Π½ΡΡΡΠ΅ Π² ΠΏΠ΅ΡΠ΅Π½ΠΈΠΈ ΠΈΡΠ΅ΠΌΠΈΡΠ΅ΡΠΊΠΎΠΉ Π±ΠΎΠ»Π΅Π·Π½ΠΈ ΡΠ΅ΡΠ΄ΡΠ° Π±Π»Π°Π³ΠΎΠ΄Π°ΡΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ Π²ΡΡΠΎΠΊΠΎΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ½ΡΡ
Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² Π»Π΅ΡΠ΅Π½ΠΈΡ, Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅ ΠΊΠΎΡΠΎΠ½Π°ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ½ΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ, Π°ΠΊΡΡΠ°Π»ΡΠ½ΡΠΌΠΈ ΠΎΡΡΠ°ΡΡΡΡ Π²ΠΎΠΏΡΠΎΡΡ ΠΎΡΠ΅Π½ΠΊΠΈ ΠΏΠΎΡΠΏΠ΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΡΠ΅ΡΠ΅Π½ΠΈΡ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ, ΠΏΠΎΠΈΡΠΊ ΡΠ°ΠΊΡΠΎΠ², Π²Π»ΠΈΡΡΡΠΈΡ
Π½Π° ΠΏΡΠΎΠ³ΡΠ΅ΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ°Π½Π½ΠΈΡ
ΠΈ ΠΏΠΎΠ·Π΄Π½ΠΈΡ
ΡΠ΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΡΡ
ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ. ΠΡΡΠ²Π»Π΅Π½ΠΈΠ΅ ΡΠ°Π½Π½ΠΈΡ
ΠΏΡΠ΅Π΄ΠΈΠΊΡΠΎΡΠΎΠ² Π½Π΅Π±Π»Π°Π³ΠΎΠΏΡΠΈΡΡΠ½ΡΡ
ΠΈΡΡ
ΠΎΠ΄ΠΎΠ² ΡΠ²Π»ΡΠ΅ΡΡΡ Π²Π°ΠΆΠ½Π΅ΠΉΡΠ΅ΠΉ Π·Π°Π΄Π°ΡΠ΅ΠΉ. ΠΠ°Π»ΠΈΡΠΈΠ΅ Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΠΈ ΠΏΠΎΡΠ΅ΠΊ Π² ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΌ ΠΏΠ΅ΡΠΈΠΎΠ΄Π΅ ΠΏΠΎΡΠ»Π΅ ΠΊΠΎΡΠΎΠ½Π°ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ½ΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠ²ΠΏΡΠ΅ΡΡΡ Π²Π°ΠΆΠ½ΡΠΌ ΡΠ°ΠΊΡΠΎΡΠΎΠΌ, ΠΏΡΠΈΠ²ΠΎΠ΄ΡΡΠΈΠΌ ΠΊ ΡΡ
ΡΠ΄ΡΠ΅Π½ΠΈΡ ΠΊΠ°ΡΠ΄ΠΈΠΎΡΠ΅Π½Π°Π»ΡΠ½ΡΡ
Π²Π·Π°ΠΈΠΌΠΎΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠΉ. Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ. ΠΡΠ΅Π½ΠΈΡΡ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½Π½ΠΎΡΡΡ Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΠΈ ΠΏΠΎΡΠ΅ΠΊ ΡΡΠ΅Π΄ΠΈ Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΈΡΠ΅ΠΌΠΈΡΠ΅ΡΠΊΠΎΠΉ Π±ΠΎΠ»Π΅Π·Π½ΡΡ ΡΠ΅ΡΠ΄ΡΠ° Π² ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΌ ΠΏΠ΅ΡΠΈΠΎΠ΄Π΅ ΠΏΠΎΡΠ»Π΅ ΠΊΠΎΡΠΎΠ½Π°ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ½ΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π²ΠΎ Π²Π·Π°ΠΈΠΌΠΎΡΠ²ΡΠ·ΠΈ Ρ Π΄ΡΡΠ³ΠΈΠΌΠΈ ΡΠ°ΠΊΡΠΎΡΠ°ΠΌΠΈ ΡΠ΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΠΎΠ³ΠΎ ΡΠΈΡΠΊΠ°
Ultrastructural and morphological characteristics of endometrial tissue receptivity in patients with reproductive failures
The aim of study was the morphological and ultrastructural features of the tissue level of the receptivity of the endometrium. There were examined 46 women with a uterine infertility due to the thin' endometrium and 45 patients with recurrent miscarriage of pregnancy associated with endometrial hypoplasia. The control group consisted of 28 fertile healthy women. A histological and ultrastructural study of the endometrium was performed using the scanning electron microscopy method during the supposed 'implantation' window on day 7 after ovulation, determined by the urinary test. Structural markers of endometrial tissue receptivity destruction are morphological features of chronic inflammation and its outcomes, or dysplastic processes, accompanied by a violation of the formation and maturation of pinopodies, separation of dense intercellular contacts and dysfunction of cells in the microenvironment.Π‘ ΡΠ΅Π»ΡΡ ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ ΠΌΠΎΡΡΠΎΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΡΠ½ΡΡ
ΠΈ ΡΠ»ΡΡΡΠ°ΡΡΡΡΠΊΡΡΡΠ½ΡΡ
ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠ΅ΠΉ ΡΠΊΠ°Π½Π΅Π²ΠΎΠΉ ΡΠ΅ΡΠ΅ΠΏΡΠΈΠ²Π½ΠΎΡΡΠΈ Β«ΡΠΎΠ½ΠΊΠΎΠ³ΠΎΒ» ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΡ ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΎ 46 ΠΆΠ΅Π½ΡΠΈΠ½ Ρ ΠΌΠ°ΡΠΎΡΠ½ΠΎΠΉ ΡΠΎΡΠΌΠΎΠΉ Π±Π΅ΡΠΏΠ»ΠΎΠ΄ΠΈΡ ΠΈ 45 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠΊ Ρ ΠΏΡΠΈΠ²ΡΡΠ½ΡΠΌ Π½Π΅Π²ΡΠ½Π°ΡΠΈΠ²Π°Π½ΠΈΠ΅ΠΌ Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΡΡΠΈ, ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½Π½ΡΠΌΠΈ Π³ΠΈΠΏΠΎΠΏΠ»Π°Π·ΠΈΠ΅ΠΉ ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΡ. ΠΠΎΠ½ΡΡΠΎΠ»ΡΠ½ΡΡ Π³ΡΡΠΏΠΏΡ ΡΠΎΡΡΠ°Π²ΠΈΠ»ΠΈ 28 ΡΠ΅ΡΡΠΈΠ»ΡΠ½ΡΡ
Π·Π΄ΠΎΡΠΎΠ²ΡΡ
ΠΆΠ΅Π½ΡΠΈΠ½. ΠΡΠΎΠ²Π΅Π΄Π΅Π½ΠΎ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΈ ΡΠ»ΡΡΡΠ°ΡΡΡΡΠΊΡΡΡΠ½ΠΎΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ ΡΠΊΠ°Π½ΠΈΡΡΡΡΠ΅ΠΉ ΡΠ»Π΅ΠΊΡΡΠΎΠ½Π½ΠΎΠΉ ΠΌΠΈΠΊΡΠΎΡΠΊΠΎΠΏΠΈΠΈ Π² ΠΏΠ΅ΡΠΈΠΎΠ΄ ΠΏΡΠ΅Π΄ΠΏΠΎΠ»Π°Π³Π°Π΅ΠΌΠΎΠ³ΠΎ Β«ΠΈΠΌΠΏΠ»Π°Π½ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎΒ» ΠΎΠΊΠ½Π° Π½Π° 7 Π΄Π΅Π½Ρ ΠΏΠΎΡΠ»Π΅ ΠΎΠ²ΡΠ»ΡΡΠΈΠΈ, ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΠ΅ΠΌΠΎΠΉ ΠΏΠΎ ΠΌΠΎΡΠ΅Π²ΠΎΠΌΡ ΡΠ΅ΡΡΡ._Π‘ΡΡΡΠΊΡΡΡΠ½ΡΠΌΠΈ ΠΌΠ°ΡΠΊΠ΅ΡΠ°ΠΌΠΈ Π½Π°ΡΡΡΠ΅Π½ΠΈΡ ΡΠΊΠ°Π½Π΅Π²ΠΎΠ³ΠΎ ΡΡΠΎΠ²Π½Ρ ΡΠ΅ΡΠ΅ΠΏΡΠΈΠ²Π½ΠΎΡΡΠΈ ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΡ ΡΠ²Π»ΡΡΡΡΡ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΈ Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π²ΠΎΡΠΏΠ°Π»Π΅Π½ΠΈΡ ΠΈ Π΅Π³ΠΎ ΠΈΡΡ
ΠΎΠ΄ΠΎΠ², Π² ΡΠ°ΠΊΠΆΠ΅ Π΄ΠΈΡΠΏΠ»Π°ΡΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΡΠΎΡΠ΅ΡΡΡ, ΡΠΎΠΏΡΠΎΠ²ΠΎΠΆΠ΄Π°ΡΡΠΈΠ΅ΡΡ Π½Π°ΡΡΡΠ΅Π½ΠΈΠ΅ΠΌ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈ ΡΠΎΠ·ΡΠ΅Π²Π°Π½ΠΈΡ ΠΏΠΈΠ½ΠΎΠΏΠΎΠ΄ΠΈΠΉ, ΡΠ°Π·ΠΎΠ±ΡΠ΅Π½ΠΈΡ ΠΏΠ»ΠΎΡΠ½ΡΡ
ΠΌΠ΅ΠΆΠΊΠ»Π΅ΡΠΎΡΠ½ΡΡ
ΠΊΠΎΠ½ΡΠ°ΠΊΡΠΎΠ² ΠΈ Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΠ΅ΠΉ ΠΊΠ»Π΅ΡΠΎΠΊ ΠΌΠΈΠΊΡΠΎΠΎΠΊΡΡΠΆΠ΅Π½ΠΈΡ